27 sierpnia, 2020
Anti-PD-L1 Monoclonal Antibodies in People Living with HIV and Cancer
Anti-PD-1 and Anti-PD-L1 Monoclonal Antibodies in People Living with HIV and Cancer
Purpose of review: Immune checkpoint inhibitors targeting the programmed cell death-1 (PD-1) pathway are a class of anti-cancer immunotherapy agents changing treatment paradigms of many cancers that occur at higher rates in people living with HIV (PLWH) than in the general population. However, PLWH have been excluded from most of the initial clinical trials with these agents.
Recent findings: Two recent prospective studies of anti-PD-1 agents, along with observational studies and a meta-analysis, have demonstrated acceptable safety in PLWH. Preliminary evidence indicates activity in a range of tumors and across CD4+ T cell counts.
Safety and preliminary activity data suggest monoclonal antibodies targeting PD-1 or its ligand, PD-L1, are generally appropriate for PLWH and cancers for which there are FDA-approved indications. Ongoing and future trials of anti-PD-1 and anti-PD-L1 therapy alone or in combination for HIV-associated cancers may further improve outcomes for this underserved population.
Human KIR2DL4 ELISA KIT |
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ELI-21303h | Lifescience Market | 96 Tests | EUR 988.8 |
KIR2DL4 |
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pro-2460 | ProSpec Tany | 1µg | EUR 60 |
Description: Recombinant Human Killer Cell Immunoglobulin-Like Receptor, 2 Domains Long Cytoplasmic Tail 4 |
KIR2DL4 |
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CSB-CL857457HU | Cusabio | 10 μg plasmid + 200μl Glycerol | Ask for price |
Human KIR2DL4 shRNA Plasmid |
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20-abx952576 | Abbexa |
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KIR2DL4 antibody |
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70R-2365 | Fitzgerald | 50 ug | EUR 560.4 |
Description: Rabbit polyclonal KIR2DL4 antibody raised against the middle region of KIR2DL4 |
KIR2DL4 Antibody |
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E309374 | EnoGene | 200ul | EUR 275 |
Description: Available in various conjugation types. |
KIR2DL4 Antibody |
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DF13591-100ul | Affinity Biosciences | 100ul | EUR 280 |
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KIR2DL4 Antibody |
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DF13591-200ul | Affinity Biosciences | 200ul | EUR 350 |
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KIR2DL4 Antibody |
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E912836 | EnoGene | 100ul | EUR 255 |
Description: Available in various conjugation types. |
KIR2DL4 Antibody |
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DF13591 | Affinity Biosciences | 100ul | EUR 280 |
Description: Human,Rat |
KIR2DL4 Antibody |
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GWB-MP022D | GenWay Biotech | 50ug | Ask for price |
NE Purified anti-human CD158d (KIR2DL4) |
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E16FHY158d-050U | EnoGene | 50 μg | EUR 845 |
Description: Available in various conjugation types. |
Human KIR2DL4 Protein, Fc Tag |
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E40KMPH4155 | EnoGene | 20ug | EUR 495 |
Human KIR2DL4 Protein, Fc Tag |
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E40KMPH4156 | EnoGene | 20ug | EUR 495 |
KIR2DL4 Recombinant Protein (Human) |
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RP017041 | ABM | 100 ug | Ask for price |
KIR2DL4 ORF Vector (Human) (pORF) |
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ORF005681 | ABM | 1.0 ug DNA | EUR 114 |
Human KIR2DL4 knockout cell line |
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ABC-KH7929 | AcceGen | 1 vial | Ask for price |
Description: Human KIR2DL4 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology. |
Human KIR2DL4 knockdown cell line |
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ABC-KD7929 | AcceGen | 1 vial | Ask for price |
Description: Human KIR2DL4 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest. |
Human KIR2DL4 Protein Lysate 20ug |
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IHUKIR2DL4PLLY20UG | Innovative research | each | EUR 213 |
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Description: Human KIR2DL4 Protein Lysate 20ug |
KIR2DL3 / KIR2DL1 / KIR2DL4 / KIR2DS4 Antibody |
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20-abx210854 | Abbexa |
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KIR2DL3 / KIR2DL1 / KIR2DL4 / KIR2DS4 Antibody |
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20-abx339417 | Abbexa |
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KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4 Antibody |
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1-CSB-PA205578 | Cusabio |
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Description: A polyclonal antibody against KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4. Recognizes KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200 |
KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4 Antibody |
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1-CSB-PA246816 | Cusabio |
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Description: A polyclonal antibody against KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4. Recognizes KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:50-1:100 |
KIR2DL4 siRNA |
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20-abx921662 | Abbexa |
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Human KIR2DL4 / CD158d Protein, Fc Tag |
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KI4-H5255 | ACROBIOSYSTEMS | 100ug | EUR 2749.9 |
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Description: Human KIR2DL4, Fc Tag (KI4-H5255) is expressed from human 293 cells (HEK293). It contains AA His 24 - His 242 (Accession # Q99706-1). |
KIR2DL4 Polyclonal Antibody |
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27806-100ul | SAB | 100ul | EUR 302.4 |
KIR2DL4 Polyclonal Antibody |
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27806-50ul | SAB | 50ul | EUR 224.4 |
KIR2DL4 Polyclonal Antibody |
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27806 | SAB | 100ul | EUR 439 |
Recombinant Human KIR2DL4 Protein, His Tag |
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E40KMH1307 | EnoGene | 20ug | EUR 495 |
Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His) |
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C310-10ug | Novoprotein | 10ug | EUR 157.2 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His) |
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C310-1mg | Novoprotein | 1mg | EUR 2739.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His) |
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C310-500ug | Novoprotein | 500ug | EUR 1935.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His) |
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C310-50ug | Novoprotein | 50ug | EUR 327.6 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His) |
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AP75042 | SAB | 1mg | EUR 3209 |
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KIR2DL4 Rabbit pAb |
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A12836-100ul | Abclonal | 100 ul | EUR 369.6 |
KIR2DL4 Rabbit pAb |
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A12836-200ul | Abclonal | 200 ul | EUR 550.8 |
KIR2DL4 Rabbit pAb |
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A12836-20ul | Abclonal | 20 ul | EUR 219.6 |
KIR2DL4 Rabbit pAb |
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A12836-50ul | Abclonal | 50 ul | EUR 267.6 |
KIR2DL4 Rabbit mAb |
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A23918 | Abclonal | 200μL | EUR 1557.4 |
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Description: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human p70 S6 Kinase 2 (Q9UBS0). |
KIR2DL4 Rabbit pAb |
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E2511314 | EnoGene | 100ul | EUR 225 |
Description: Available in various conjugation types. |
KIR2DL4 sgRNA CRISPR Lentivector set (Human) |
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K1150301 | ABM | 3 x 1.0 ug | EUR 406.8 |
KIR2DL4 Protein Vector (Human) (pPM-C-HA) |
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PV022723 | ABM | 500 ng | EUR 394.8 |
KIR2DL4 cloning plasmid |
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CSB-CL857457HU-10ug | Cusabio | 10ug | EUR 279.6 |
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Description: A cloning plasmid for the KIR2DL4 gene. |
KIR2DL4 Protein Vector (Human) (pPB-C-His) |
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PV022721 | ABM | 500 ng | EUR 394.8 |
KIR2DL4 Protein Vector (Human) (pPB-N-His) |
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PV022722 | ABM | 500 ng | EUR 394.8 |
KIR2DL4 Protein Vector (Human) (pPM-C-His) |
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PV022724 | ABM | 500 ng | EUR 394.8 |
KIR2DL4 Blocking Peptide |
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33R-9831 | Fitzgerald | 100 ug | EUR 216 |
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of KIR2DL4 antibody, catalog no. 70R-2365 |
OAEE00659-100T - KIR2DL4 Antibody |
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OAEE00659-100T | Aviva Systems Biology | 100tests | EUR 299 |
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OAEE00660-100T - KIR2DL4 Antibody |
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OAEE00660-100T | Aviva Systems Biology | 100tests | EUR 299 |
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OAGA02475-100UL - KIR2DL4 Antibody |
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OAGA02475-100UL | Aviva Systems Biology | 100ul | EUR 369 |
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OAEE00101-100UG - KIR2DL4 Antibody |
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OAEE00101-100UG | Aviva Systems Biology | 0.1mg | EUR 259 |
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KIR2DL4 Recombinant Protein |
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91-290 | ProSci | 0.05 mg | EUR 556.8 |
Description: Killer cell immunoglobulin-like receptor 2DL4(KIR2DL4) is a Single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16. |
Recombinant Human KIR2DL4 Protein, His, Insect-1ug |
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QP12489-1ug | EnQuireBio | 1ug | EUR 186 |
Recombinant Human KIR2DL4 Protein, His, Insect-5ug |
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QP12489-5ug | EnQuireBio | 5ug | EUR 241.2 |
Recombinant Human KIR2DL4 Protein, His, Insect-50ug |
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QP12489-50ug | EnQuireBio | 50ug | EUR 1513.2 |
KIR2DL4 Polyclonal Conjugated Antibody |
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C27806 | SAB | 100ul | EUR 476.4 |
KIR2DL4 sgRNA CRISPR Lentivector (Human) (Target 1) |
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K1150302 | ABM | 1.0 ug DNA | EUR 184.8 |
KIR2DL4 sgRNA CRISPR Lentivector (Human) (Target 2) |
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K1150303 | ABM | 1.0 ug DNA | EUR 184.8 |
KIR2DL4 sgRNA CRISPR Lentivector (Human) (Target 3) |
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K1150304 | ABM | 1.0 ug DNA | EUR 184.8 |
Recombinant Human CD158D/KIR2DL4 Protein, His Tag |
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E40KMH335 | EnoGene | 20ug | EUR 495 |
KIR2DL4 (untagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 1 |
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SC126103 | Origene Technologies GmbH | 10 µg | Ask for price |
KIR2DL4 (untagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 2 |
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SC319875 | Origene Technologies GmbH | 10 µg | Ask for price |
KIR2DL4 (untagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 3 |
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SC315741 | Origene Technologies GmbH | 10 µg | Ask for price |
Human KIR2DL4 Recombinant Protein C-6 His Tag Lyophilized |
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IHUKIR2DL4RC6HISLY50UG | Innovative research | each | EUR 640 |
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Description: Human KIR2DL4 Recombinant Protein C-6 His Tag Lyophilized |
KIR2DL4 (GFP-tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 3 |
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RG214254 | Origene Technologies GmbH | 10 µg | Ask for price |
KIR2DL4 (GFP-tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 1 |
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RG214354 | Origene Technologies GmbH | 10 µg | Ask for price |
KIR2DL4 (GFP-tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 2 |
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RG208307 | Origene Technologies GmbH | 10 µg | Ask for price |
KIR2DL4 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each |
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SR320789 | Origene Technologies GmbH | 2 nmol | Ask for price |
Lenti ORF particles, KIR2DL4 (Myc-DDK tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), |
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RC214254L3V | Origene Technologies GmbH | 200 µl | Ask for price |
Lenti ORF particles, KIR2DL4 (Myc-DDK tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), |
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RC214354L3V | Origene Technologies GmbH | 200 µl | Ask for price |
ARP42025_P050-25UL - KIR2DL4 Antibody - middle region |
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ARP42025_P050-25UL | Aviva Systems Biology | 25ul | EUR 99 |
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KIR2DL4 (Myc-DDK-tagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 2 |
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RC208307 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF particles, KIR2DL4 (mGFP-tagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), trans |
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RC208307L4V | Origene Technologies GmbH | 200 µl | Ask for price |
KIR2DL4 (Myc-DDK-tagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 3 |
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RC214254 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF particles, KIR2DL4 (mGFP-tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), tra |
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RC214254L4V | Origene Technologies GmbH | 200 µl | Ask for price |
KIR2DL4 (Myc-DDK-tagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 1 |
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RC214354 | Origene Technologies GmbH | 10 µg | Ask for price |
Lenti ORF particles, KIR2DL4 (mGFP-tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), tra |
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RC214354L4V | Origene Technologies GmbH | 200 µl | Ask for price |
OCOA15270-20UG - KIR2DL4 Protein Lysate |
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OCOA15270-20UG | Aviva Systems Biology | 20ug | EUR 169 |
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OCOA14196-20UG - KIR2DL4 Protein Lysate |
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OCOA14196-20UG | Aviva Systems Biology | 20ug | EUR 169 |
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KIR2DL4 Over-expression Lysate Product |
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GWB-F8A916 | GenWay Biotech | 0.1 mg | Ask for price |
CD70 antibody-drug conjugate as a potential therapeutic agent for uterine leiomyosarcoma
Background: Uterine leiomyosarcoma is a rare and aggressive gynecologic malignancy originating in the myometrium of the uterine corpus that tends to recur even after complete surgical excision. Current therapeutic agents have only modest effects on uterine leiomyosarcoma.
Although antibodies and antibody-drug conjugates (ADCs) have been recognized as useful targeted therapies for other cancers, no study has yet evaluated the effects of this approach on uterine leiomyosarcoma.
Objective: To examine the activity of tumoral cluster of differentiation 70 (CD70) in uterine leiomyosarcoma and assess the antitumor activity of CD70-ADC treatment in uterine leiomyosarcoma.
Study design: Target membrane proteins were screened by profiling and comparing membrane protein expression in three uterine leiomyosarcoma cell lines (SK-UT-1, SK-LMS-1, and SKN) and normal uterine myometrium cells using the isobaric tags for relative and absolute quantitation labeling method.
Western blotting, fluorescence-activated cell sorting analyses, and immunohistochemistry were used to examine CD70 expression in the membrane proteins in uterine leiomyosarcoma cell lines and clinical samples. We developed an ADC with a monoclonal antibody of the target membrane protein linked to monomethyl auristatin F (MMAF) and investigated its antitumor effects against uterine leiomyosarcoma (in-vitro, in-vivo, and in patient-derived xenograft [PDX] models).
Results: CD70 was identified as a specific antigen highly expressed in uterine leiomyosarcoma cell lines. Of the three uterine leiomyosarcoma cell lines, CD70 expression was confirmed in SK-LMS-1 cells by western blotting and fluorescence-activated cell sorting analysis. CD70 overexpression was observed in 19 of 21 (90.5%) tumor specimens from women with uterine leiomyosarcoma.
To generate CD70-ADC, anti-CD70 monoclonal antibody was conjugated with a novel derivative of MMAF. CD70-ADC showed significant antitumor effects on SK-LMS-1 cells (IC50 0.120 nM) and no antitumor effects on CD70-negative uterine leiomyosarcoma cells.
CD70-ADC significantly inhibited tumor growth in the SK-LMS-1 xenograft mouse model (tumor volume: 129.8 versus 285.5 mm3, 54.5% relative reduction, P<0.001) and PDX mouse model (tumor volume: 128.1 versus 837.7 mm3, 84.7% relative reduction, P<0.001).
Conclusion: Uterine leiomyosarcoma tumors highly express CD70 and targeted therapy with CD70-ADC may have a potential therapeutic implication in the treatment of uterine leiomyosarcoma.
Promising clinical performance of pretargeted immuno-PET with anti-CEA bispecific antibody and gallium-68-labelled IMP-288 peptide for imaging colorectal cancer metastases: a pilot study
Introduction: This pilot study evaluated the imaging performance of pretargeted immunological positron emission tomography (immuno-PET) using an anti-carcinoembryonic antigen (CEA) recombinant bispecific monoclonal antibody (BsMAb), TF2 and the [68Ga]Ga-labelled HSG peptide, IMP288, in patients with metastatic colorectal carcinoma (CRC).
Patients and methods: Patients requiring diagnostic workup of CRC metastases or in case of elevated CEA for surveillance were prospectively studied. They had to present with elevated CEA serum titre or positive CEA tumour staining by immunohistochemistry of a previous biopsy or surgical specimen.
All patients underwent endoscopic ultrasound (EUS), chest-abdominal-pelvic computed tomography (CT), abdominal magnetic resonance imaging (MRI) and positron emission tomography using [18F]fluorodeoxyglucose (FDG-PET).
For immuno-PET, patients received intravenously 120 nmol of TF2 followed 30 h later by 150 MBq of [68Ga]Ga-labelled IMP288, both I.V. The gold standard was histology and imaging after 6-month follow-up.
Results: Eleven patients were included. No adverse effects were reported after BsMAb and peptide injections. In a per-patient analysis, immuno-PET was positive in 9/11 patients. On a per-lesion analysis, 12 of 14 lesions were positive with immuno-PET.
Median SUVmax, MTV and TLG were 7.65 [3.98-13.94, SD 3.37], 8.63 cm3 [1.98-46.64; SD 14.83] and 37.90 cm3 [8.07-127.5; SD 43.47] respectively for immuno-PET lesions. Based on a per-lesion analysis, the sensitivity, specificity, positive-predictive value and negative-predictive value were, respectively, 82%, 25%, 82% and 25% for the combination of EUS/CT/MRI; 76%, 67%, 87% and 33% for FDG-PET; and 88%, 100%, 100% and 67% for immuno-PET. Immuno-PET had an impact on management in 2 patients.
Conclusion: This pilot study showed that pretargeted immuno-PET using anti-CEA/anti-IMP288 BsMAb and a [68Ga]Ga-labelled hapten was safe and feasible, with promising diagnostic performance.
Trial registration: ClinicalTrials.gov NCT02587247 Registered 27 October 2015.
Human Resistin Antibody |
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GWB-F7AAE4 | GenWay Biotech | 0.1 mg | Ask for price |
Biotinylated Anti-Human Resistin |
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GWB-BIG87D | GenWay Biotech | 1 kit | Ask for price |
Human Resistin (RETN) |
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1-CSB-EP019573HU | Cusabio |
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Description: Recombinant Human Resistin(RETN) expressed in E.coli |
Anti- Resistin Mouse Antibody |
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GWB-11F9B7 | GenWay Biotech | 0.1 mg | Ask for price |
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Recombinant Human Resistin |
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7-01519 | CHI Scientific | 5µg | Ask for price |
Recombinant Human Resistin |
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7-01520 | CHI Scientific | 25µg | Ask for price |
Recombinant Human Resistin |
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7-01521 | CHI Scientific | 1mg | Ask for price |
RECOMBINANT HUMAN RESISTIN |
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GWB-F4A137 | GenWay Biotech | 0.02 mg | Ask for price |
Canine Resistin(Resistin) ELISA Kit |
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QY-E70171 | Qayee Biotechnology | 96T | EUR 511.2 |
human Resistin ELISA KIT |
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201-12-0339 | SunredBio | 96 tests | EUR 528 |
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Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
Human Resistin ELISA kit |
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55R-1714 | Fitzgerald | 1 kit | EUR 805.2 |
Description: ELISA kit for the detection of Human Resistin in the research laboratory |
Human Resistin ELISA kit |
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55R-2127 | Fitzgerald | 96 tests | EUR 919.2 |
Description: ELISA Kit for detection of Resistin in the research laboratory |
Human Resistin ELISA kit |
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55R-E50 | Fitzgerald | 96 wells | EUR 1413.6 |
Description: ELISA kit for the detection of Human Resistin in the research laboratory |
human Resistin ELISA KIT |
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CN-04165H1 | ChemNorm | 96T | EUR 530.4 |
human Resistin ELISA KIT |
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CN-04165H2 | ChemNorm | 48T | EUR 351.6 |
Human Resistin ELISA KIT |
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CSB-E06884h-24T | Cusabio | 1 plate of 24 wells | EUR 198 |
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Description: Quantitativesandwich ELISA kit for measuring Human Resistin in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
Human Resistin ELISA KIT |
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1-CSB-E06884h | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Human Resistin in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
Human Resistin ELISA kit |
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E01R0351-192T | BlueGene | 192 tests | EUR 1524 |
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Description: A competitive ELISA for quantitative measurement of Human Resistin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Resistin ELISA kit |
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E01R0351-48 | BlueGene | 1 plate of 48 wells | EUR 624 |
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Description: A competitive ELISA for quantitative measurement of Human Resistin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Resistin ELISA kit |
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E01R0351-96 | BlueGene | 1 plate of 96 wells | EUR 822 |
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Description: A competitive ELISA for quantitative measurement of Human Resistin in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species. |
Human Resistin ELISA kit |
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LF-EK50441 | Abfrontier | 1×96T | EUR 790.8 |
Human Resistin ELISA Kit |
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LF-EK70021 | Abfrontier | 1×96T | EUR 625.2 |
Human Resistin ELISA Kit |
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EHR0358 | Abclonal | 96Tests | EUR 625.2 |
Human Resistin ELISA Kit |
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RK00139 | Abclonal | 96 Tests | EUR 625.2 |
Human Resistin ELISA KIT |
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EKC40240-48T | Biomatik Corporation | 48T | EUR 412.02 |
Human Resistin ELISA KIT |
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EKC40240-5x96T | Biomatik Corporation | 5x96T | EUR 2795.85 |
Human Resistin ELISA KIT |
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EKC40240-96T | Biomatik Corporation | 96T | EUR 588.6 |
Human Resistin ELISA Kit |
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SL1530Hu | Sunlong | 96 Tests | EUR 468 |
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Human Resistin ELISA Kit |
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E28L0045 | EnoGene | 96T | EUR 666.67 |
Human Resistin ELISA KIT |
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E42EH-93 | EnoGene | 96T/48T | Ask for price |
Human Resistin ELISA Kit |
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E16HE0035 | EnoGene | 96T | EUR 833.33 |
Human Resistin ELISA KIT |
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E16HE0035-048 | EnoGene | 48 wells | EUR 295 |
Human Resistin ELISA KIT |
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E16HE0035-096 | EnoGene | 96 wells | EUR 395 |
Human Resistin ELISA kit |
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E22-HC136.48 | EnoGene | 48T | EUR 295 |
Human Resistin ELISA kit |
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E22-HC136.96 | EnoGene | 96T | EUR 395 |
Human Resistin ELISA kit |
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E01A7519 | BlueGene | 96T | EUR 700 |
Description: ELISA |
Human Resistin ELISA Kit |
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GWB-SKR059 | GenWay Biotech | 96 Tests | Ask for price |
Human Resistin ELISA Kit |
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GWB-ZZD207 | GenWay Biotech | 1x96 well plate | Ask for price |
Resistin, human recombinant |
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4559-100 | Biovision | each | EUR 874.8 |
Resistin, human recombinant |
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4559-1000 | Biovision | each | EUR 6127.2 |
Resistin, human recombinant |
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4559-25 | Biovision | each | EUR 307.2 |
Resistin (Recombinant) Human |
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GWB-8EE40A | GenWay Biotech | 0.025 mg | Ask for price |
Resistin (Human) ELISA Kit |
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EKA51875-5x96T | Biomatik Corporation | 5x96T | Ask for price |
Resistin (Human) ELISA Kit |
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EKA51875-96T | Biomatik Corporation | 96T | EUR 446.9 |
Polyclonal Anti- Resistin Antibody |
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GWB-BBP350 | GenWay Biotech | 0.1 mg | Ask for price |
Human Resistin (RETN) Protein |
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20-abx068871 | Abbexa |
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Human Resistin (RETN) Protein |
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20-abx651562 | Abbexa |
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Human Resistin (RETN) Protein |
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abx670217-25ug | Abbexa | 25 ug | EUR 661.2 |
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Resistin |
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GT15031 | Neuromics | 100 ug | EUR 662.4 |
Resistin |
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cyt-456 | ProSpec Tany | 5µg | EUR 60 |
Description: Recombinant Human Resistin |
Resistin |
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RA19059 | Neuromics | 100 ul | EUR 451.2 |
Resistin |
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AP78694 | SAB | 1mg | EUR 2640 |
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Resistin |
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AP78695 | SAB | 1mg | EUR 2640 |
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Resistin |
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AP89468 | SAB | 1mg | EUR 2640 |
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Recombinant Human Resistin(RETN) |
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AP70712 | SAB | 1mg | EUR 1978 |
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Recombinant Human Resistin (RETN) |
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CSB-EP019573HU | Cusabio | 2058 mg | Ask for price |
Recombinant Human Resistin (RETN) |
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Z100805 | ABM | 25 µg | EUR 85 |
Description: Resistin was identified by screening for genes that are induced during the differentiation of adipocytes but down-regulated in mature adipocytes. Resistin gene expression is induced during the differentiation of adipocytes. Resistin circulates in mouse serum, and its level is increased markedly in obesity. Adipocytes secrete resistin as a unique signaling molecule that may be the hormone potentially linking obesity to type II diabetes, which is characterized by target-tissue resistance to insulin. TNF-alpha is a negative regulator of Resistin gene expression and inhibits Resistin mRNA expression and protein secretion by 70-90% in 3T3-L1 adipocytes. |
Recombinant Human Resistin (RETN) |
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Z100809 | ABM | 1.0 mg | EUR 1500 |
Description: Resistin was identified by screening for genes that are induced during the differentiation of adipocytes but down-regulated in mature adipocytes. Resistin gene expression is induced during the differentiation of adipocytes. Resistin circulates in mouse serum, and its level is increased markedly in obesity. Adipocytes secrete resistin as a unique signaling molecule that may be the hormone potentially linking obesity to type II diabetes, which is characterized by target-tissue resistance to insulin. TNF-alpha is a negative regulator of Resistin gene expression and inhibits Resistin mRNA expression and protein secretion by 70-90% in 3T3-L1 adipocytes. |
Human Resistin (RETN) CLIA Kit |
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abx195057-96tests | Abbexa | 96 tests | EUR 990 |
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Human Resistin (RETN) CLIA Kit |
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20-abx492128 | Abbexa |
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ELISA kit for Human Resistin |
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KET6029-48T | Abbkine | 48T | EUR 242.4 |
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Description: Quantitative sandwich ELISA for measuring Human Resistin in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Resistin |
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KET6029-5platesof96wells | Abbkine | 5 plates of 96 wells | EUR 1292.4 |
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Description: Quantitative sandwich ELISA for measuring Human Resistin in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Resistin |
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KET6029-96T | Abbkine | 96T | EUR 346.8 |
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Description: Quantitative sandwich ELISA for measuring Human Resistin in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids. |
ELISA kit for Human Resistin |
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EK2351 | SAB | 96 tests | EUR 542.4 |
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Resistin in samples from serum, plasma, tissue homogenates and other biological fluids. |
Human Resistin(REN) Elisa Kit |
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EK710243 | AFG Bioscience LLC | 96 Wells | EUR 0.74 |
Human Resistin Antibody (Biotin Conjugate) |
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32138-05121 | AssayPro | 150 ug | EUR 442.8 |
Human Resistin (RETN) ELISA Kit |
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abx252068-96tests | Abbexa | 96 tests | EUR 764.4 |
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Human Resistin (RETN) ELISA Kit |
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abx050199-96tests | Abbexa | 96 tests | EUR 801.6 |
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Human Resistin (RETN) ELISA Kit |
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abx051478-96tests | Abbexa | 96 tests | EUR 801.6 |
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Human Resistin (RETN) ELISA Kit |
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abx575492-96tests | Abbexa | 96 tests | EUR 764.4 |
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Human Resistin, RETN ELISA Kit |
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DEIA139 | Creative Diagnostics | 15 Plates | EUR 2889.6 |
Description: Human RETN ELISA development kit contains the key components required for the quantitative measurement of natural and/or recombinant RETN in a sandwich ELISA format within the range of 16-2,000 pg/mL. Using the ELISA protocol described below, this kit provides sufficient reagents to assay RETN in approximately 1,500 ELISA plate wells. |
Human Resistin, RETN ELISA Kit |
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DEIA221 | Creative Diagnostics | 96T | EUR 1020 |
Description: This assay is a sandwich Enzyme Linked-Immuno-Sorbent Assay (ELISA). It is developed for quantitative measurement of Human RETN in serum, plasma and other biological fluids. |
Human Resistin (RETN) ELISA Kit |
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DLR-RETN-Hu-48T | DL Develop | 48T | EUR 529.2 |
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Description: A sandwich quantitative ELISA assay kit for detection of Human Resistin (RETN) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Human Resistin (RETN) ELISA Kit |
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DLR-RETN-Hu-96T | DL Develop | 96T | EUR 684 |
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Description: A sandwich quantitative ELISA assay kit for detection of Human Resistin (RETN) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids. |
Human Resistin (RETN) ELISA Kit |
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20-abx152952 | Abbexa |
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Human Resistin(RETN)ELISA Kit |
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GA-E0355HM-48T | GenAsia Biotech | 48T | EUR 346.8 |
Human Resistin(RETN)ELISA Kit |
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GA-E0355HM-96T | GenAsia Biotech | 96T | EUR 559.2 |
Human Resistin, RETN ELISA KIT |
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ELI-02884h | Lifescience Market | 96 Tests | EUR 988.8 |
Human Resistin (RETN) ELISA Kit |
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RD-RETN-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 523.2 |
Human Resistin (RETN) ELISA Kit |
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RD-RETN-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 721.2 |
Human Resistin (RETN) ELISA Kit |
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RDR-RETN-Hu-48Tests | Reddot Biotech | 48 Tests | EUR 546 |
Human Resistin (RETN) ELISA Kit |
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RDR-RETN-Hu-96Tests | Reddot Biotech | 96 Tests | EUR 754.8 |