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27 sierpnia, 2020

Antibodies monitoring in a bunch of residents in a long run care facility

By Pawel

Anti SARS-CoV-2 antibodies monitoring in a bunch of residents in a long run care facility throughout COVID-19 pandemic peak

Targets Scientific laboratories performs a key function in screening, analysis and containment of the Coronavirus 2019 an infection epidemic. The etiological analysis presupposes the isolation of virus genetic materials within the affected person’s organic pattern however laboratory diagnostics additionally make use of looking chance for IgG, IgM lessons antibodies. The traits of the antibody response aren’t but fully clear.
Strategies This research describes a serological monitoring of topics, aged nursing care residence friends, interested in a really giant an infection outbreak. After first nasopharyngeal swab, all of the optimistic topics (43) have been monitored for the persistence of the virus an infection by nasopharyngeal swab after 20 days (16-24), 32 days (28-36) and after 49 days (47-50). On the identical time, through the second (day 32) and third (day 49) comply with up, all of the friends have been investigated for IgM and IgG anti SARS-CoV-2 antibodies, by utilizing a quantitative chemiluminescence methodology.
Outcomes Thirty two days after performing the primary diagnostic swab, 39 of 43 sufferers (90%) had IgG increased than the reduce off worth. After 49 days the 4 sufferers with detrimental IgG have been nonetheless detrimental. The comparability of the degrees of IgG-Ab between the controls reveals a big lower in concentrations (-10%).
Conclusions Our research confirms that in most sufferers affected by COVID-19 there’s a typical antibody response with IgG-Ab current in 90% of nursing care COVID-19 optimistic residence friends. For IgM-Ab solely 23% of examined topics have been optimistic on the 32nd and 49th day of sickness, at all times in parallel with the IgG-Ab positivity.
automatyka-robotyka

automatyka-robotyka

Anti-IL-17 antibody
PAab04224 100 ug
EUR 463.2

Recombinant Human IL-17
SJB09-03 25µg/vial
EUR 307.2

Anti-IL-17 alpha antibody
STJ93683 200 µl
EUR 236.4
Description: Rabbit polyclonal to IL-17Ralpha.

Human Interleukin 17 (IL-17) CLIA Kit
abx195860-96tests 96 tests
EUR 990
  • Shipped within 5-12 working days.

Human Interleukin 17,IL-17 ELISA Kit
201-12-0143 96 tests
EUR 528
  • This Interleukin 17 ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Interleukin 17,IL-17 ELISA Kit
CN-03335H1 96T
EUR 520.8

Human Interleukin 17,IL-17 ELISA Kit
CN-03335H2 48T
EUR 340.8

Human Interleukin 17(IL-17)ELISA Kit
GA-E0081HM-48T 48T
EUR 346.8

Human Interleukin 17(IL-17)ELISA Kit
GA-E0081HM-96T 96T
EUR 559.2

Human Interleukin 17(IL-17)ELISA Kit
QY-E04323 96T
EUR 433.2

Human Interleukin 17,IL-17 ELISA Kit
YLA1538HU-48T 48T
EUR 435

Human Interleukin 17,IL-17 ELISA Kit
YLA1538HU-96T 96T
EUR 562.5

IL-17 Interleukin-17 Human Recombinant Protein
PROTQ16552-1 Regular: 25ug
EUR 380.4
Description: Interleukin-17A Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain containing a total of 264 amino acids (2 chains of 132 aa) and having a molecular mass of 31kDa.  ;The IL-17 is purified by proprietary chromatographic techniques.

Recombinant Human IL-17 (IL-17A) Protein
PROTQ16552-4 25ug
EUR 380.4
Description: The originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules.  Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles.  The six known members of this family, IL-17A through IL-17F, are secreted as homodimers.  IL-17A exhibits cross-species bioactivity between human and murine cells.  Recombinant human IL-17A is a 31.3 kDa disulfide-linked homodimer of two 137 amino acid polypeptide chains.

human IL-17, His tag
E410A10-100 100μg
EUR 1152

IL-17 (Human) ELISA Kit
E4628-100 each
EUR 874.8

Human IL-17 ELISA kit
LF-EK50201 1×96T
EUR 777.6

IL-17 ELISA KIT|Human
EF006939 96 Tests
EUR 826.8

Interleukin 17 (IL-17) Antibody
abx234224-100ug 100 ug
EUR 610.8
  • Shipped within 5-12 working days.

Interleukin 17 (IL-17) Antibody
abx234225-100ug 100 ug
EUR 577.2
  • Shipped within 5-12 working days.

IL-17 Antibody
5176-100 each
EUR 405.6

IL-17 Antibody
4877-002mg 0.02 mg
EUR 206.18
  • Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Description: IL-17 Antibody: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-κB and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.

IL-17 Antibody
4877-01mg 0.1 mg
EUR 523.7
  • Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Description: IL-17 Antibody: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-κB and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.

IL-17 Antibody
4887-002mg 0.02 mg
EUR 206.18
  • Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Description: IL-17 Antibody: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-κB and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.

IL-17 Antibody
4887-01mg 0.1 mg
EUR 523.7
  • Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Description: IL-17 Antibody: Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-κB and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.

IL-17 Antibody
24784-100ul 100ul
EUR 468

IL-17 Antibody
24789-100ul 100ul
EUR 468

IL-17 Antibody
F42568-0.4ML 0.4 ml
EUR 322.15
Description: The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

IL-17 Antibody
R35097-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Interleukin 17A; IL17A

IL-17 Antibody
R36188-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Interleukin 17A antibody, IL17A, CTLA8

CLIA kit for Human IL-17 (Interleukin 17)
E-CL-H0104 1 plate of 96 wells
EUR 700.8
  • Gentaur's IL-17 CLIA kit utilizes the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Human IL-17 . Standards or samples are added to the micro CLIA plate wells and combined with th
  • Show more
Description: A sandwich CLIA kit for quantitative measurement of Human IL-17 (Interleukin 17) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human IL-17 (Interleukin 17)
E-EL-H0105 1 plate of 96 wells
EUR 452.4
  • Gentaur's IL-17 ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human IL-17. Standards or samples are added to the micro ELISA plate wells and combined with
  • Show more
Description: A sandwich ELISA kit for quantitative measurement of Human IL-17 (Interleukin 17) in samples from Serum, Plasma, Cell supernatant

Human Interleukin 17 (IL-17) Detection Assay Kit
6808 1 kit
EUR 580.26
Description: Human Interleukin 17 (IL-17) Detection Assay Kit

IL-17
E5-00007 1mg
EUR 1152

IL-17
MO15110 500 ug
EUR 1092

IL-17
EF014060 96 Tests
EUR 826.8

IL-17
PR27113 5 ug
EUR 229.2

IL-17 Interleukin-17 Human Recombinant Protein, HEK
PROTQ16552 Regular: 10ug
EUR 380.4
Description: IL-17 Human Recombinant produced in HEK cells is a glycosylated homodimer, having a molecular weight range of 30-35kDa due to glycosylation.;The IL-17 is purified by proprietary chromatographic techniques.

IL-17/IL-17A
E21-021 10ug
EUR 411.6

ELISA kit for Human IL-17
KET6022-48T 48T
EUR 242.4
  • The protein encoded by IL-17 gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxyge
  • Show more
Description: Quantitative sandwich ELISA for measuring Human IL-17 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human IL-17
KET6022-5platesof96wells 5 plates of 96 wells
EUR 1292.4
  • The protein encoded by IL-17 gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxyge
  • Show more
Description: Quantitative sandwich ELISA for measuring Human IL-17 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Human IL-17
KET6022-96T 96T
EUR 346.8
  • The protein encoded by IL-17 gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxyge
  • Show more
Description: Quantitative sandwich ELISA for measuring Human IL-17 in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Human IL-17 ELISA kit (4X96T)
LF-EK50202 4×96T
EUR 2641.2

CymaxTM Human IL-17 ELISA Kit
LF-EK0295 1×96T
EUR 477.6

Human IL-17 PicoKine ELISA Kit
EK0430 96 wells
EUR 510
Description: For quantitative detection of human IL-17 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

IL-17 Interleukin-17 Human Recombinant Protein, His Tag
PROTQ16552-2 Regular: 10ug
EUR 380.4
Description: Interleukin-17A Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 132 amino acids fragment (24-155) having a molecular weight of 19.62kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. ;The IL-17A His is purified by proprietary chromatographic techniques.

Human Interleukin 17A (IL-17A/IL-17) ELISA Kit
CSB-E12819h-24T 1 plate of 24 wells
EUR 198
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 17A (IL-17A/IL-17) in samples from serum, urine, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Interleukin 17A (IL-17A/IL-17) ELISA Kit
1-CSB-E12819h
  • EUR 964.8
  • EUR 6118.8
  • EUR 3244.8
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 17A (IL-17A/IL-17) in samples from serum, urine, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Polyclonal IL-17 Antibody
APR06508G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IL-17 . This antibody is tested and proven to work in the following applications:

Polyclonal IL-17 Antibody
APR06512G 0.1 mg
EUR 790.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human IL-17 . This antibody is tested and proven to work in the following applications:

Bovine Interleukin 17(IL-17)
QY-E60069 96T
EUR 511.2

IL-17 Peptide
4877P 0.05 mg
EUR 197.7
Description: (NT) IL-17 peptide

IL-17 Peptide
4887P 0.05 mg
EUR 197.7
Description: (IN) IL-17 peptide

Human Interleukin-17,IL-17A ELISA Kit
ELA-E1700h 96 Tests
EUR 988.8

Genorise® Anti-canine IL-17 Polyclonal Antibody
GR105162 100 ug
EUR 438

IL-17 receptor D antibody
22228-100ul 100ul
EUR 468

Recombinant Human IL-17 Receptor A/IL-17RA/CD217 (C-Fc)
CI53-10ug 10ug
EUR 120
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human IL-17 Receptor A/IL-17RA/CD217 (C-Fc)
CI53-1mg 1mg
EUR 1094.4
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human IL-17 Receptor A/IL-17RA/CD217 (C-Fc)
CI53-500ug 500ug
EUR 850.8
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human IL-17 Receptor A/IL-17RA/CD217 (C-Fc)
CI53-50ug 50ug
EUR 242.4
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Human IL-17A(Interleukin 17 A) ELISA Kit
EH3267 96T
EUR 571.5
  • Detection range: 31.25-2000 pg/ml
  • Uniprot ID: Q16552
  • Alias: IL-17(Interleukin 17)/CTLA-8/IL17A/IL-17CTLA-8/IL17interleukin-17A/interleukin 17A
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human Interleukin-17 A (IL-17A) ELISA Kit
LF-EK60049 1×96T
EUR 948

Genorise® Biotinylated Anti-equine IL-17 Polyclonal Antibody
GR109027 50 mg
EUR 398

Genorise® Biotinylated Anti-canine IL-17 Polyclonal Antibody
GR109179 50 mg
EUR 398

IL-17 Recombinant Protein
91-616 0.05 mg
EUR 588.3
Description: Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.

IL-17 Recombinant Protein
91-015 0.05 mg
EUR 437.1
Description: Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.

A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interplay

COVID-19 brought on by SARS-CoV-2 has develop into a worldwide pandemic requiring the event of interventions for the prevention or therapy to curtail mortality and morbidity. No vaccine to spice up mucosal immunity, or as a therapeutic, has but been developed to SARS-CoV-2. On this research, we uncover and characterize a cross-reactive human IgA monoclonal antibody, MAb362.
  • MAb362 binds to each SARS-CoV and SARS-CoV-2 spike proteins and competitively blocks ACE2 receptor binding, by overlapping the ACE2 structural binding epitope. Moreover, MAb362 IgA neutralizes each pseudotyped SARS-CoV and SARS-CoV-2 in 293 cells expressing ACE2.
  • When transformed to secretory IgA, MAb326 additionally neutralizes genuine SARS-CoV-2 virus whereas the IgG isotype reveals no neutralization.
  • Our outcomes counsel that SARS-CoV-2 particular IgA antibodies, corresponding to MAb362, could present efficient immunity towards SARS-CoV-2 by inducing mucosal immunity throughout the respiratory system, a probably crucial characteristic of an efficient vaccine.

Separation of monoclonal antibody monomer-dimer mixtures by gradient elution with ceramic hydroxyapatite

Modeling the chromatographic separations of proteins at manufacturing scale is vital since downstream processing prices are sometimes dominant. At such scales, the columns are extremely overloaded heightening the problem of predicting efficiency.
On this work, the separation of a monoclonal antibody monomer-dimer combination is performed by gradient elution chromatography with ceramic hydroxyapatite (CHT) columns Kind I and Kind II below overloaded situations.
Phosphate gradients are proven to be preferable over sodium chloride gradients because the latter end in undesirable pH transitions generated throughout the column itself. Utilizing sodium phosphate gradients separation is obtained with each CHT varieties, attaining roughly 90% restoration at 99% monomer purity beginning with a combination containing 30% dimer at whole protein masses as much as 30 mg/mL. Due to its increased binding capability, even increased loadings will be obtained with CHT Kind I with out monomer breakthrough.
A hybrid mannequin is developed to explain the separation. The mannequin, based mostly on an empirical description of two-component, aggressive isotherms at low sodium phosphate focus coupled with the stoichiometric displacement mannequin at increased sodium phosphate concentrations, is in good settlement with the experiments utilizing the linear driving drive (LDF) approximation to explain adsorption/desorption kinetics.

The identical LDF price coefficient predicts the separation at loadings between 0.eight and 30 mg/mL. The mannequin developed on this work can be utilized as a common instrument to optimize working situations, perceive what components restrict efficiency, and evaluate completely different working modes.

Rabbit TGFR ELISA Kit
ERTT0062 96Tests
EUR 625.2

Monkey TGFR ELISA Kit
EMKT0062 96Tests
EUR 625.2

Bovine TGFR ELISA Kit
EBT0062 96Tests
EUR 625.2

Canine TGFR ELISA Kit
ECT0062 96Tests
EUR 625.2

Porcine TGFR ELISA Kit
EPT0062 96Tests
EUR 625.2

Chicken TGFR ELISA Kit
ECKT0062 96Tests
EUR 625.2

Anserini TGFR ELISA Kit
EAT0062 96Tests
EUR 625.2

Guinea Pig TGFR ELISA Kit
EGT0062 96Tests
EUR 625.2

Recombinant Human ALK-1 Protein
RP00978 5 μg
EUR 163.2

Recombinant Human ALK-1 Protein
VAng-2860Lsx-10g 10 µg
EUR 736.8
Description: Recombinant Human ALK-1 was expressed in Sf9 Insect Cells. (Uniprot ID: P37023)

Recombinant Human ALK-1 Protein
VAng-2860Lsx-1mg 1 mg
EUR 16605.6
Description: Recombinant Human ALK-1 was expressed in Sf9 Insect Cells. (Uniprot ID: P37023)

Goat anti Human IgG (Alk Phos)
43C-CB0963 1 mg
EUR 433.2
Description: Goat anti Human IgG secondary antibody (Alk Phos)

Goat anti Human IgG (Alk Phos)
43C-CB0978 1 mg
EUR 483.6
Description: Goat anti Human IgG secondary antibody (Alk Phos)

Goat anti Human IgM (Alk Phos)
43C-CB0999 1 mg
EUR 456
Description: Goat anti Human IgM secondary antibody (Alk Phos)

Goat anti Human IgG (Alk Phos)
43R-1169 1 mg
EUR 223.2
Description: Goat anti Human IgG secondary antibody (Alk Phos)

Goat anti Human IgG (Alk Phos)
43R-1175 1 mg
EUR 268.8
Description: Goat anti Human IgG secondary antibody (Alk Phos)

Goat anti Human IgG (Alk Phos)
43R-1192 1 mg
EUR 315.6
Description: Goat anti Human IgG secondary antibody (Alk Phos)

Goat anti Human IgG (Alk Phos)
43R-1204 500 ug
EUR 355.2
Description: Goat anti Human IgG secondary antibody  (Alk Phos)

Goat anti Human IgG (Alk Phos)
43R-IG012alk 1 ml
EUR 658.8
Description: Goat anti Human IgG secondary antibody (Alk Phos)

Goat anti Human IgG (Alk Phos)
43R-IG165ALK 1 mg
EUR 268.8
Description: Goat anti Human IgG secondary antibody (Alk Phos)

ALK-1 Polyclonal Antibody
ABP52913-003ml 0.03ml
EUR 189.6
  • Immunogen information: Synthesized peptide derived from the N-terminal region of human ALK-1
  • Applications tips:
Description: A polyclonal antibody for detection of ALK-1 from Human, Mouse, Rat. This ALK-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human ALK-1

ALK-1 Polyclonal Antibody
ABP52913-01ml 0.1ml
EUR 346.8
  • Immunogen information: Synthesized peptide derived from the N-terminal region of human ALK-1
  • Applications tips:
Description: A polyclonal antibody for detection of ALK-1 from Human, Mouse, Rat. This ALK-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human ALK-1

ALK-1 Polyclonal Antibody
ABP52913-02ml 0.2ml
EUR 496.8
  • Immunogen information: Synthesized peptide derived from the N-terminal region of human ALK-1
  • Applications tips:
Description: A polyclonal antibody for detection of ALK-1 from Human, Mouse, Rat. This ALK-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the N-terminal region of human ALK-1

ALK-1 Polyclonal Antibody
ABP57032-003ml 0.03ml
EUR 189.6
  • Immunogen information: Synthesized peptide derived from the Internal region of human ALK-1 at AA range: 170-250
  • Applications tips:
Description: A polyclonal antibody for detection of ALK-1 from Human, Mouse, Rat. This ALK-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ALK-1 at AA range: 170-250

ALK-1 Polyclonal Antibody
ABP57032-01ml 0.1ml
EUR 346.8
  • Immunogen information: Synthesized peptide derived from the Internal region of human ALK-1 at AA range: 170-250
  • Applications tips:
Description: A polyclonal antibody for detection of ALK-1 from Human, Mouse, Rat. This ALK-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ALK-1 at AA range: 170-250

ALK-1 Polyclonal Antibody
ABP57032-02ml 0.2ml
EUR 496.8
  • Immunogen information: Synthesized peptide derived from the Internal region of human ALK-1 at AA range: 170-250
  • Applications tips:
Description: A polyclonal antibody for detection of ALK-1 from Human, Mouse, Rat. This ALK-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human ALK-1 at AA range: 170-250

ALK-1 Polyclonal Antibody
41591-100ul 100ul
EUR 302.4

ALK-1 Polyclonal Antibody
41591-50ul 50ul
EUR 224.4

ALK-1 Polyclonal Antibody
ES8031-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against ALK-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

ALK-1 Polyclonal Antibody
ES8031-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against ALK-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

ALK-1 Polyclonal Antibody
ES3912-100ul 100ul
EUR 334.8
Description: A Rabbit Polyclonal antibody against ALK-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

ALK-1 Polyclonal Antibody
ES3912-50ul 50ul
EUR 248.4
Description: A Rabbit Polyclonal antibody against ALK-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Rabbit anti Human IgG (Alk Phos)
43C-CB0949 1 mg
EUR 526.8
Description: Rabbit anti Human IgG secondary antibody (Alk Phos)

Rabbit anti Human IgG (Alk Phos)
43C-CB0956 1 mg
EUR 450
Description: Rabbit anti Human IgG secondary antibody (Alk Phos)

Rabbit anti Human IgG (Alk Phos)
43C-CB0970 1 mg
EUR 450
Description: Rabbit anti Human IgG secondary antibody (Alk Phos)

Rabbit anti Human IgM (Alk Phos)
43C-CB9106 1 mg
EUR 522
Description: Rabbit anti Human IgM secondary antibody (Alk Phos)

Rabbit anti Human IgA (Alk Phos)
43C-CB9120 1 mg
EUR 475.2
Description: Rabbit anti Human IgA secondary antibody (Alk Phos)

Anti-ALK-1 antibody
STJ91563 200 µl
EUR 236.4
Description: Rabbit polyclonal to ALK-1.

Anti-ALK-1 antibody
STJ96547 200 µl
EUR 236.4
Description: Rabbit polyclonal to ALK-1.

Nori® Human ALK-1 ELISA Kit
GR111542 96-well
EUR 461

Human ALK and LTK ligand 1 (ALKAL1)
1-CSB-EP757795HU
  • EUR 606
  • EUR 318
  • EUR 2192.4
  • EUR 919.2
  • EUR 1461.6
  • EUR 402
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 25.5 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Human ALK and LTK ligand 1(ALKAL1) expressed in E.coli

ELISA kit for Human ALK-1/ACVRL1
EK5715 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human ALK-1/ACVRL1 in samples from serum, plasma, tissue homogenates and other biological fluids.

ALK-IN-1
HY-13464 100mg
EUR 472.8

Human ALK-1/ACVRL1 PicoKine ELISA Kit
EK1518 96 wells
EUR 510
Description: For quantitative detection of human ALK-1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

ALK inhibitor 1
HY-15357 50mg
EUR 1712.4

Goat anti Human IgG Fc (Alk Phos)
43-I24 100 ug
EUR 198
Description: Goat anti Human IgG Fc secondary antibody (Alk Phos)

Goat anti Human Kappa Chain (Alk Phos)
43C-CB9127 1 mg
EUR 500.4
Description: Goat anti Human Kappa Chain secondary antibody (Alk Phos)

Goat anti Human kappa chain (Alk Phos)
43R-1257 500 ug
EUR 482.4
Description: Goat anti Human kappa chain secondary antibody (Alk Phos)

Goat anti Human Lambda Chain (Alk Phos)
43C-CB9134 1 mg
EUR 500.4
Description: Goat anti Human Lambda Chain secondary antibody (Alk Phos)

ALK-1 Polyclonal Conjugated Antibody
C41591 100ul
EUR 476.4

Goat anti Human IgG (H + L) (Alk Phos)
43C-CB0921 1 mg
EUR 205.2
Description: Goat anti Human IgG (H + L) secondary antibody (Alk Phos)

Goat anti Human IgG (H + L) (Alk Phos)
43C-CB0928 1 mg
EUR 417.6
Description: Goat anti Human IgG (H + L) secondary antibody (Alk Phos)

Goat anti Human IgG (H + L) (Alk Phos)
43C-CB0935 1 mg
EUR 543.6
Description: Goat anti Human IgG (H + L) secondary antibody (Alk Phos)

Goat anti Human IgG (H + L) (Alk Phos)
43R-1145 1 mg
EUR 268.8
Description: Goat anti Human IgG (H + L) secondary antibody (Alk Phos)

Goat anti Human IgG (H + L) (Alk Phos)
43R-1157 500 ug
EUR 268.8
Description: Goat anti Human IgG (H + L) secondary antibody (Alk Phos)

Goat anti Human IgG (H + L) (Alk Phos)
43R-1163 500 ug
EUR 315.6
Description: Goat anti Human IgG (H + L) secondary antibody (Alk Phos)

Recombinant Human ALK-1 Protein (aa 22-503)
VAng-2854Lsx-100g 100 µg
EUR 8440.8
Description: Recombinant Human ALK-1 was expressed in cell free expression systems. (Uniprot ID: P37023)

Recombinant Human ALK-1 Protein (aa 22-503)
VAng-2854Lsx-50g 50 µg
EUR 5454
Description: Recombinant Human ALK-1 was expressed in cell free expression systems. (Uniprot ID: P37023)

Recombinant Human ALK-1 Protein (aa 22-118)
VAng-2856Lsx-1mg 1 mg
EUR 3393.6
Description: Recombinant Human ALK-1 was expressed in E. coli. (Uniprot ID: P37023)

Recombinant Human ALK-1 Protein (aa 22-118)
VAng-2856Lsx-200g 200 µg
EUR 2205.6
Description: Recombinant Human ALK-1 was expressed in E. coli. (Uniprot ID: P37023)

Recombinant Human ALK-1 Protein (aa 22-118)
VAng-2856Lsx-500g 500 µg
EUR 2419.2
Description: Recombinant Human ALK-1 was expressed in E. coli. (Uniprot ID: P37023)

ALK-1 Recombinant Protein
92-565 0.05 mg
EUR 374.1
Description: Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF- beta superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angiogenesis during embryogenesis, wound healing, and tumor growth. ALK-1 has a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine rich region preceding the kinase-domain, and a C-terminal tail with other activin receptor-like kinase proteins. ALK-1 is mainly expressed in endothelial cells regulating proliferation and migration in vitro and angiogenesis in vivo. Mutations in ALK-1 as well as in endoglin are associated with hereditary hemorrhagic telangiectasia (HHT), suggesting ALK-1 plays a critical role for in the control of blood vessel development or repair.

Anti-ALK Antibody Clone ALK/1503, Unconjugated-20ug
238-MSM3-P0 20ug
EUR 279.6

Anti-ALK Antibody Clone ALK/1503, Unconjugated-100ug
238-MSM3-P1 100ug
EUR 513.6

Rabbit anti Human IgG (H + L) (Alk Phos)
43-I23 1 mg
EUR 435.6
Description: Rabbit anti Human IgG (H + L) secondary antibody (Alk Phos)
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