cDNA
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27 sierpnia, 2020

Equine Influenza Virus-Neutralising Antibody Responses Induced by Vaccination and Infection

By Pawel

Evaluation of a Pseudotyped Virus Neutralisation Test for the Measurement of Equine Influenza Virus-Neutralising Antibody Responses Induced by Vaccination and Infection

Equine influenza is a major respiratory disease of horses that is largely controlled by vaccination in some equine populations. Virus-neutralising antibodies, the mainstay of the protective immune response, are problematic in assaying for equine influenza virus, as most strains do not replicate efficiently in cell culture. Surrogate measures of protective antibody responses include the haemagglutination inhibition (HI) test and single radial haemolysis (SRH) assay.
  • For this study, a pseudotyped virus, bearing an envelope containing the haemagglutinin (HA) from the Florida clade 2 equine influenza virus strain A/equine/Richmond/1/07 (H3N8), was generated to measure HA-specific neutralising antibodies in serum samples (n = 134) from vaccinated or experimentally-infected ponies using a pseudotyped virus neutralization test (PVNT).
  • Overall, the results of PVNT were in good agreement with results from the SRH assay (100% sensitivity, 68.53% specificity) and HI test (99.2% sensitivity, 49.03% specificity).
  • The PVNT was apparently more sensitive than either the SRH assay or the HI test, which could be advantageous for studying the antibody kinetics, particularly when antibody levels are low.
  • Nevertheless, further studies are required to determine whether a protective antibody level can be defined for the SRH assay and to ascertain the inter-laboratory reproducibility.
  • In conclusion, the PVNT efficiently measures neutralising antibodies after immunization and/or experimental infection in the natural host, and may complement existing antibody assays.
cDNA

cDNA

Human Galectin-1 (LGALS1)
1-CSB-EP012882HUb1
  • EUR 456
  • EUR 256.8
  • EUR 1570.8
  • EUR 672
  • EUR 1047.6
  • EUR 314.4
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 19.6 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Human Galectin-1(LGALS1) expressed in E.coli

Human Galectin-3(Galectin-3)ELISA Kit
YLA0216HU-48T 48T
EUR 435

Human Galectin-3(Galectin-3)ELISA Kit
YLA0216HU-96T 96T
EUR 562.5

Recombinant Human Galectin-1
7-00427 10µg Ask for price

Recombinant Human Galectin-1
7-00428 50µg Ask for price

Recombinant Human Galectin-1
7-00429 1mg Ask for price

Recombinant Human Galectin-1
HEOPP-0710 10ug Ask for price

Human Galectin 1 Protein
20-abx066725
  • EUR 744
  • EUR 326.4
  • EUR 2230.8
  • EUR 878.4
  • EUR 543.6
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Anti Human Galectin-3 Polyclonal Antibody
KH040 each
EUR 778.8
Description: The Anti Human Galectin-3 Polyclonal Antibody is available in Europe and for worldwide shipping via Gentaur.

Galectin-1, human recombinant
4648-10 each
EUR 170.4

Galectin-1, human recombinant
4648-1000 each
EUR 1977.6

Galectin-1, human recombinant
4648-50 each
EUR 314.4

Human Galectin 1 ELISA kit
E01G0038-192T 192 tests
EUR 1524
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin 1 ELISA kit
E01G0038-48 1 plate of 48 wells
EUR 624
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin 1 ELISA kit
E01G0038-96 1 plate of 96 wells
EUR 822
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1 (LGALS1) Protein
abx670211-50ug 50 ug
EUR 661.2
  • Shipped within 1 week.

ELISA kit for Human Galectin-1
EK5323 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Galectin-1 in samples from serum, plasma, tissue homogenates and other biological fluids.

Galectin-1 Antibody
3596-100 each
EUR 379.2

Galectin-1 Antibody
3596-30T each
EUR 175.2

Galectin-1 Antibody
R34524-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Lectin, galactose binding, soluble 1; Lgals1

Galectin-1 Antibody
R34565-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Lgals1

Anti-human Galectin-3 antibody
STJ15100163 250 µg
EUR 403.2
Description: This monoclonal antibody is for studies of antigen expression in cells and tissue sections using immunocytochemistry and immunoprecipitation

Human Galectin 8 Antibody
33159-05111 150 ug
EUR 313.2

Human Galectin 2 Antibody
33165-05111 150 ug
EUR 313.2

Human Galectin 13 Antibody
33175-05111 150 ug
EUR 313.2

Human Galectin 10 Antibody
32652-05111 150 ug
EUR 313.2

Recombinant Human Galectin-1 Protein
PROTP09382-1 50ug
EUR 380.4
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.

Recombinant Human Galectin-1 Protein
RP00007 20 μg
EUR 208.8

anti- Galectin-3 antibody
FNab03316 100µg
EUR 606.3
  • Recommended dilution: WB: 1:500-1:5000
  • IP: 1:200-1:2000
  • IHC: 1:20-1:200
  • IF: 1:10-1:100
  • Immunogen: lectin, galactoside-binding, soluble, 3
  • Uniprot ID: P17931
  • Research Area: Cardiovascular, Cancer, Immunology, Neuroscience, Cell Division and Prolife
  • Show more
Description: Antibody raised against Galectin-3

anti- Galectin-3 antibody
FNab03317 100µg
EUR 658.5
  • Recommended dilution: WB: 1:1000-1:5000
  • IHC: 1:50-1:200
  • IF: 1:20-1:200
  • Immunogen: lectin, galactoside-binding, soluble, 3
  • Uniprot ID: P17931
  • Research Area: Cardiovascular, Cancer, Immunology, Neuroscience, Cell Division and Proliferation
Description: Antibody raised against Galectin-3

anti- Galectin-7 antibody
FNab03318 100µg
EUR 606.3
  • Recommended dilution: WB: 1:1000-1:4000
  • IHC: 1:20-1:200
  • Immunogen: lectin, galactoside-binding, soluble, 7B
  • Uniprot ID: P47929
  • Gene ID: 653499
  • Research Area: Immunology, Cancer, Immunology, Neuroscience, Cell Division and Proliferation
Description: Antibody raised against Galectin-7

Human Galectin 1 (GAL1) CLIA Kit
20-abx190336
  • EUR 9493.2
  • EUR 5058
  • EUR 1167.6
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Human Galectin 1 (GAL1) CLIA Kit
abx196676-96tests 96 tests
EUR 990
  • Shipped within 5-12 working days.

Human Galectin 1 (GAL1)CLIA Kit
SCA321Hu-10x96wellstestplate 10x96-wells test plate
EUR 6777.36
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Galectin 1 (GAL1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1)CLIA Kit
SCA321Hu-1x48wellstestplate 1x48-wells test plate
EUR 663.31
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Galectin 1 (GAL1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1)CLIA Kit
SCA321Hu-1x96wellstestplate 1x96-wells test plate
EUR 896.16
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Galectin 1 (GAL1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1)CLIA Kit
SCA321Hu-5x96wellstestplate 5x96-wells test plate
EUR 3672.72
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Galectin 1 (GAL1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1) CLIA Kit
4-SCA321Hu
  • EUR 6837.6
  • EUR 3673.2
  • EUR 896.4
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Galectin 1 Clia kit. Alternative names of the recognized antigen: LGALS1
  • GBP
  • HLBP14
  • Galaptin
  • Lectin, Galactoside-Binding Soluble 1
  • 14 kDa laminin-binding protein
  • Lactose-binding lectin 1
  • Putative MAPK-activating protein PM12
  • S-L
  • Show more
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1)Serum, plasma and other biological fluids

Human Galectin-1(LGALS1) ELISA kit
CSB-EL012882HU-24T 1 plate of 24 wells
EUR 198
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human Galectin-1 (LGALS1) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Galectin-1(LGALS1) ELISA kit
1-CSB-EL012882HU
  • EUR 964.8
  • EUR 6118.8
  • EUR 3244.8
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human Galectin-1(LGALS1) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Galectin-1(LGALS1) ELISA kit
E01G0448-192T 192 tests
EUR 1524
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1(LGALS1) ELISA kit
E01G0448-48 1 plate of 48 wells
EUR 624
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1(LGALS1) ELISA kit
E01G0448-96 1 plate of 96 wells
EUR 822
  • Kit contents: 1. MICROTITER PLATE * 1 2. ENZYME CONJUGATE*1 vial 3. STANDARD A*1 vial 4. STANDARD B*1 vial 5. STANDARD C*1 vial 6. STANDARD D*1 vial 7. STANDARD E*1 vial 8. STANDARD F*1 vial 9. SUBSTRATE A*1 vial 10. SUBSTRATE B*1 vial 11. STOP SOLUT
  • Show more
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1 (Gal-1) Antibody (Biotin Conjugate)
30005-05121 150 ug
EUR 442.8

Human Galectin 1 (GAL1) ELISA kit
201-12-3227 96 tests
EUR 528
  • This Galectin 1 ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Galectin 1 (GAL1) ELISA Kit
DLR-GAL1-Hu-48T 48T
EUR 574.8
  • Should the Human Galectin 1 (GAL1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Galectin 1 (GAL1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit
DLR-GAL1-Hu-96T 96T
EUR 745.2
  • Should the Human Galectin 1 (GAL1) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Galectin 1 (GAL1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Galectin 1 ELISA Kit (GAL1)
RK01436 96 Tests
EUR 625.2

Human Galectin 1 (GAL1) ELISA Kit
RDR-GAL1-Hu-48Tests 48 Tests
EUR 600

Human Galectin 1 (GAL1) ELISA Kit
RDR-GAL1-Hu-96Tests 96 Tests
EUR 830.4

Human Galectin 1(GAL1)ELISA Kit
QY-E04196 96T
EUR 433.2

Human Galectin 1 (GAL1) ELISA Kit
RD-GAL1-Hu-48Tests 48 Tests
EUR 573.6

Human Galectin 1 (GAL1) ELISA Kit
RD-GAL1-Hu-96Tests 96 Tests
EUR 794.4

Human Galectin 1 (GAL1) ELISA Kit
SEA321Hu-10x96wellstestplate 10x96-wells test plate
EUR 4091.29
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Galectin 1 (GAL1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit
SEA321Hu-1x48wellstestplate 1x48-wells test plate
EUR 442.1
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Galectin 1 (GAL1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit
SEA321Hu-1x96wellstestplate 1x96-wells test plate
EUR 580.15
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Galectin 1 (GAL1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit
SEA321Hu-5x96wellstestplate 5x96-wells test plate
EUR 2250.68
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Galectin 1 (GAL1) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit
4-SEA321Hu
  • EUR 4152
  • EUR 2191.2
  • EUR 580.8
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Galectin 1 elisa. Alternative names of the recognized antigen: LGALS1
  • GBP
  • HLBP14
  • Galaptin
  • Lectin, Galactoside-Binding Soluble 1
  • 14 kDa laminin-binding protein
  • Lactose-binding lectin 1
  • Putative MAPK-activating protein PM12
  • S-Lac
  • Show more
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Galectin 1 (GAL1) in samples from serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Galectin 1 (GAL1) ELISA Kit
RD-GAL1-Hu-48T 48T
EUR 411.8
  • sandwich
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit
RD-GAL1-Hu-96T 96T
EUR 588.3
  • sandwich
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Galectin 1 (GAL1) ELISA kit
YLA3564HU-48T 48T
EUR 435

Human Galectin 1 (GAL1) ELISA kit
YLA3564HU-96T 96T
EUR 562.5

Human Galectin 1 (GAL1) ELISA Kit
RDR-GAL1-Hu-48T 48T
EUR 432.39
  • sandwich
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit
RDR-GAL1-Hu-96T 96T
EUR 617.72
  • sandwich
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit
DLR-GAL1-Hu 96T
EUR 422
  • 0.29ng/mL
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit
DL-GAL1-Hu 96T
EUR 402
  • sandwich
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Galectin-1 PicoKine ELISA Kit
EK0762 96 wells
EUR 510
Description: For quantitative detection of human Galectin-1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Galectin 1 (GAL1) Polyclonal Antibody (Human)
4-PAA321Hu01
  • EUR 278.4
  • EUR 2742
  • EUR 688.8
  • EUR 346.8
  • EUR 249.6
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Met1~Asp135
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Human Galectin 1 (GAL1)

Galectin 1 antibody
70R-GR002 100 ug
EUR 571.2
Description: Affinity purified Rabbit polyclonal Galectin 1 antibody

Galectin 1 antibody
70R-11939 100 ug
EUR 483.6
Description: Rabbit polyclonal Galectin 1 antibody

Galectin 1 antibody
70R-13963 100 ug
EUR 386.4
Description: Affinity purified Rabbit polyclonal Galectin 1 antibody

Galectin 1 antibody
70R-49997 100 ul
EUR 292.8
Description: Purified Polyclonal Galectin 1 antibody

Galectin 1 Antibody
49673-100ul 100ul
EUR 399.6

Galectin 1 Antibody
49673-50ul 50ul
EUR 286.8

Galectin 1 Antibody
DF8089 200ul
EUR 420

Galectin 1 Antibody
DF2383 200ul
EUR 420

Galectin 1 Antibody
R31924 100 ug
EUR 356.15
Description: Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creatingimmune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process.

Galectin 1 Antibody
R32841 100 ug
EUR 356.15
Description: Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creating immune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process.

Galectin 1 Antibody
R32842 100 ug
EUR 356.15
Description: Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-1 may act as an autocrine negative growth factor that regulates cell proliferation. Galectin-1 expression in Hodgkin Lymphoma has also been shown to mediate immunosuppression of CD8+ T-cells. It is thought to play a role in creating immune tolerance in pregnancy. It has been found that Galectin-1-mediated production of IL6 may assist in augmenting the innate immune response against NiV. Galectin-1 may also be a significant factor that augments the efficiency of the HIV-1 infection process.

Human LGALS1/ Galectin-1 ELISA Kit
E1450Hu 1 Kit
EUR 644.4

Novel Caffeic Acid Phenethyl Ester-Mortalin Antibody Nanoparticles Offer Enhanced Selective Cytotoxicity to Cancer Cells

Caffeic acid phenethyl ester (CAPE) is a key bioactive ingredient of honeybee propolis and is claimed to have anticancer activity. Since mortalin, a hsp70 chaperone, is enriched in a cancerous cell surface, we recruited a unique cell internalizing anti-mortalin antibody (MotAb) to generate mortalin-targeting CAPE nanoparticles (CAPE-MotAb). Biophysical and biomolecular analyses revealed enhanced anticancer activity of CAPE-MotAb both in in vitro and in vivo assays.

We demonstrate that CAPE-MotAb cause a stronger dose-dependent growth arrest/apoptosis of cancer cells through the downregulation of Cyclin D1-CDK4, phospho-Rb, PARP-1, and anti-apoptotic protein Bcl2. Concomitantly, a significant increase in the expression of p53, p21WAF1, and caspase cleavage was obtained only in CAPE-MotAb treated cells.

We also demonstrate that CAPE-MotAb caused a remarkably enhanced downregulation of proteins critically involved in cell migration. In vivo tumor growth assays for subcutaneous xenografts in nude mice also revealed a significantly enhanced suppression of tumor growth in the treated group suggesting that these novel CAPE-MotAb nanoparticles may serve as a potent anticancer nanomedicine.

Evaluation of a Pseudotyped Virus Neutralisation Test for the Measurement of Equine Influenza Virus-Neutralising Antibody Responses Induced by Vaccination and Infection

Equine influenza is a major respiratory disease of horses that is largely controlled by vaccination in some equine populations. Virus-neutralizing antibodies, the mainstay of the protective immune response, are problematic in assaying for equine influenza virus, as most strains do not replicate efficiently in cell culture. Surrogate measures of protective antibody responses include the haemagglutination inhibition (HI) test and single radial haemolysis (SRH) assay.
For this study, a pseudotyped virus, bearing an envelope containing the haemagglutinin (HA) from the Florida clade 2 equine influenza virus strain A/equine/Richmond/1/07 (H3N8), was generated to measure HA-specific neutralising antibodies in serum samples (n = 134) from vaccinated or experimentally-infected ponies using a pseudotyped virus neutralization test (PVNT).
Overall, the results of PVNT were in good agreement with results from the SRH assay (100% sensitivity, 68.53% specificity) and HI test (99.2% sensitivity, 49.03% specificity). The PVNT was apparently more sensitive than either the SRH assay or the HI test, which could be advantageous for studying the antibody kinetics, particularly when antibody levels are low.
Nevertheless, further studies are required to determine whether a protective antibody level can be defined for the SRH assay and to ascertain the inter-laboratory reproducibility. In conclusion, the PVNT efficiently measures neutralising antibodies after immunization and/or experimental infection in the natural host, and may complement existing antibody assays.

Mouse Podoplanin (PDPN) Protein
20-abx650139
  • EUR 777.6
  • EUR 326.4
  • EUR 2331.6
  • EUR 910.8
  • EUR 560.4
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Mouse Podoplanin (PDPN) CLIA Kit
20-abx493858
  • EUR 9567.6
  • EUR 5095.2
  • EUR 1177.2
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Mouse Podoplanin (PDPN) ELISA Kit
20-abx154564
  • EUR 8853.6
  • EUR 4719.6
  • EUR 1093.2
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Mouse Podoplanin (PDPN) ELISA Kit
abx571749-96tests 96 tests
EUR 943.2
  • Shipped within 5-12 working days.

Mouse Podoplanin (PDPN) ELISA Kit
DLR-PDPN-Mu-48T 48T
EUR 632.4
  • Should the Mouse Podoplanin (PDPN) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
DLR-PDPN-Mu-96T 96T
EUR 825.6
  • Should the Mouse Podoplanin (PDPN) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin, Pdpn ELISA KIT
ELI-06723m 96 Tests
EUR 1038

Mouse Podoplanin (PDPN) ELISA Kit
SEC719Mu-10x96wellstestplate 10x96-wells test plate
EUR 5834.88
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Podoplanin (PDPN) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
SEC719Mu-1x48wellstestplate 1x48-wells test plate
EUR 585.7
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Podoplanin (PDPN) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
SEC719Mu-1x96wellstestplate 1x96-wells test plate
EUR 785.28
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Podoplanin (PDPN) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
SEC719Mu-5x96wellstestplate 5x96-wells test plate
EUR 3173.76
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Podoplanin (PDPN) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Podoplanin (PDPN) in tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
4-SEC719Mu
  • EUR 5895.6
  • EUR 3114
  • EUR 786
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Podoplanin elisa. Alternative names of the recognized antigen: GP40
  • GP36
  • Gp38
  • HT1A-1
  • OTS8
  • PA2.26
  • T1A
  • T1A-2
  • Aggrus
  • Glycoprotein 36
  • PA2.26 antigen
  • T1-alpha
  • Lung Type I Cell Membrane Associated Glycoprotein
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Podoplanin (PDPN) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Podoplanin (PDPN) ELISA Kit
RD-PDPN-Mu-48Tests 48 Tests
EUR 639.6

Mouse Podoplanin (PDPN) ELISA Kit
RD-PDPN-Mu-96Tests 96 Tests
EUR 888

Mouse Podoplanin (PDPN) ELISA Kit
RDR-PDPN-Mu-48Tests 48 Tests
EUR 668.4

Mouse Podoplanin (PDPN) ELISA Kit
RDR-PDPN-Mu-96Tests 96 Tests
EUR 928.8

Mouse Podoplanin(PDPN)ELISA kit
QY-E21215 96T
EUR 433.2

Mouse Podoplanin (PDPN) ELISA Kit
RDR-PDPN-Mu-48T 48T
EUR 487.52
  • sandwich
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
RDR-PDPN-Mu-96T 96T
EUR 696.47
  • sandwich
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
RD-PDPN-Mu-48T 48T
EUR 464.3
  • sandwich
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
RD-PDPN-Mu-96T 96T
EUR 663.3
  • sandwich
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Podoplanin (PDPN)ELISA kit
YLA0596MO-48T 48T
EUR 465

Mouse Podoplanin (PDPN)ELISA kit
YLA0596MO-96T 96T
EUR 600

Mouse Podoplanin (PDPN) ELISA Kit
DL-PDPN-Mu 96T
EUR 453
  • sandwich
Description: tissue homogenates, cell lysates or other biological fluids.

Mouse Podoplanin (PDPN) ELISA Kit
DLR-PDPN-Mu 96T
EUR 475
  • 0.055ng/mL
Description: tissue homogenates, cell lysates or other biological fluids.

Podoplanin
MO47016 100 ul
EUR 418.8

Recombinant Mouse Podoplanin (C-Fc)
CU73-1mg 1mg
EUR 2008.8
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)
CU73-500ug 500ug
EUR 1399.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)
CU73-50ug 50ug
EUR 327.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Mouse Podoplanin (C-Fc)
CU73-10ug 10ug
EUR 157.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

ELISA kit for Mouse Podoplanin (PDPN)
KTE70775-48T 48T
EUR 398.4
  • Podoplanin is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a d
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Podoplanin (PDPN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Podoplanin (PDPN)
KTE70775-5platesof96wells 5 plates of 96 wells
EUR 2538
  • Podoplanin is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a d
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Podoplanin (PDPN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Podoplanin (PDPN)
KTE70775-96T 96T
EUR 646.8
  • Podoplanin is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a d
  • Show more
Description: Quantitative sandwich ELISA for measuring Mouse Podoplanin (PDPN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Podoplanin (PDPN) Polyclonal Antibody (Mouse)
4-PAC719Mu01
  • EUR 301.2
  • EUR 3091.2
  • EUR 768
  • EUR 379.2
  • EUR 258
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PDPN (Gly23~Val138)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN)

Podoplanin antibody
10R-7662 100 ug
EUR 754.8
Description: Mouse monoclonal Podoplanin antibody

Podoplanin antibody
10R-7663 100 ug
EUR 754.8
Description: Hamster monoclonal Podoplanin antibody

Podoplanin antibody
10R-7664 100 ug
EUR 754.8
Description: Mouse monoclonal Podoplanin antibody

Podoplanin antibody
10R-P133a 100 ug
EUR 608.4
Description: Mouse monoclonal Podoplanin antibody

Podoplanin antibody
10R-P155a 100 ug
EUR 651.6
Description: Hamster monoclonal Podoplanin antibody

Podoplanin antibody
70R-PR007 100 ug
EUR 506.4
Description: Affinity purified Rabbit polyclonal Podoplanin antibody

Podoplanin antibody
70R-11540 100 ug
EUR 632.4
Description: Rabbit polyclonal Podoplanin antibody

Podoplanin Antibody
49474-100ul 100ul
EUR 399.6

Podoplanin Antibody
49474-50ul 50ul
EUR 286.8

Podoplanin antibody
70R-13952 100 ug
EUR 366
Description: Affinity purified Rabbit polyclonal Podoplanin antibody

Podoplanin antibody
70R-6816 50 ug
EUR 560.4
Description: Rabbit polyclonal Podoplanin antibody raised against the N terminal of PDPN

Podoplanin antibody
70R-6817 50 ug
EUR 560.4
Description: Rabbit polyclonal Podoplanin antibody raised against the middle region of PDPN

Podoplanin antibody
70R-50819 100 ul
EUR 292.8
Description: Purified Polyclonal Podoplanin antibody

Podoplanin Antibody
DF12456 200ul
EUR 420

Podoplanin Antibody
P1051-01m 0.1m
EUR 250.8

Podoplanin Antibody
P1051-1ml 1ml
EUR 1129.2

Podoplanin Antibody
R33852-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: PDPN; AGGRUS; GP36; GP40; Gp38; HT1A-1; OTS8; PA2.26

Podoplanin Antibody
R20464-0.1ML 100ul
EUR 409

ELISA kit for Mouse PDPN (Podoplanin)
E-EL-M2409 1 plate of 96 wells
EUR 640.8
  • Gentaur's PDPN ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse PDPN. Standards or samples are added to the micro ELISA plate wells and combined with th
  • Show more
Description: A sandwich ELISA kit for quantitative measurement of Mouse PDPN (Podoplanin) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Mouse PDPN (Podoplanin)
ELK7080 1 plate of 96 wells
EUR 518.4
  • The microtiter plate provided in this kit has been pre-coated with an antibody specific to Podoplanin (PDPN). Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody specific to Podoplanin (PDPN
  • Show more
Description: A sandwich ELISA kit for detection of Podoplanin from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Anti-D2-40/Podoplanin antibody
STJ190048 200 µl
EUR 236.4
Description: Unconjugated Mouse monoclonal to D2-40/Podoplanin (7D1)

Anti-D2-40 Podoplanin antibody
STJ16100360 1 mL
EUR 1482

Podoplanin (PDPN) Polyclonal Antibody (Mouse), PE
4-PAC719Mu01-PE
  • EUR 361.2
  • EUR 3254.4
  • EUR 921.6
  • EUR 454.8
  • EUR 236.4
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PDPN (Gly23~Val138)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with PE.

Podoplanin (PDPN) Polyclonal Antibody (Mouse), APC
4-PAC719Mu01-APC
  • EUR 421.2
  • EUR 4038
  • EUR 1122
  • EUR 538.8
  • EUR 266.4
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PDPN (Gly23~Val138)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with APC.

Podoplanin (PDPN) Polyclonal Antibody (Mouse), Cy3
4-PAC719Mu01-Cy3
  • EUR 512.4
  • EUR 5334
  • EUR 1446
  • EUR 668.4
  • EUR 304.8
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PDPN (Gly23~Val138)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with Cy3.

Podoplanin (PDPN) Polyclonal Antibody (Mouse), HRP
4-PAC719Mu01-HRP
  • EUR 385.2
  • EUR 3519.6
  • EUR 992.4
  • EUR 486
  • EUR 250.8
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PDPN (Gly23~Val138)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with HRP.

Podoplanin (PDPN) Polyclonal Antibody (Mouse), FITC
4-PAC719Mu01-FITC
  • EUR 361.2
  • EUR 3254.4
  • EUR 921.6
  • EUR 454.8
  • EUR 236.4
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PDPN (Gly23~Val138)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Podoplanin (PDPN). This antibody is labeled with FITC.

Podoplanin (PDPN) Antibody
20-abx137407
  • EUR 844.8
  • EUR 393.6
  • EUR 276
  • 100 ug
  • 20 ug
  • 5 ug
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Antibody
abx236598-100ug 100 ug
EUR 661.2
  • Shipped within 5-12 working days.

Podoplanin (PDPN) Antibody
abx236599-100ug 100 ug
EUR 661.2
  • Shipped within 5-12 working days.

Podoplanin (PDPN) Antibody
20-abx174125
  • EUR 1028.4
  • EUR 526.8
  • 1 mg
  • 200 ug
  • Please enquire.

Podoplanin (PDPN) Antibody
20-abx174126
  • EUR 1095.6
  • EUR 560.4
  • 1 mg
  • 200 ug
  • Please enquire.

Podoplanin (PDPN) Antibody
20-abx178065
  • EUR 1479.6
  • EUR 710.4
  • 1 mg
  • 200 ug
  • Please enquire.

Podoplanin (PDPN) Antibody
20-abx178066
  • EUR 1562.4
  • EUR 744
  • 1 mg
  • 200 ug
  • Please enquire.

Podoplanin (PDPN) Antibody
20-abx178067
  • EUR 1696.8
  • EUR 794.4
  • 1 mg
  • 200 ug
  • Please enquire.

Podoplanin (PDPN) Antibody
20-abx211099
  • EUR 493.2
  • EUR 360
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Antibody
20-abx114559
  • EUR 878.4
  • EUR 477.6
  • 150 ul
  • 50 ul
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Antibody
20-abx129101
  • EUR 510
  • EUR 159.6
  • EUR 1446
  • EUR 693.6
  • EUR 393.6
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Podoplanin (PDPN) Antibody
20-abx131102
  • EUR 526.8
  • EUR 159.6
  • EUR 1479.6
  • EUR 710.4
  • EUR 393.6
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.

Podoplanin (PDPN) Antibody
20-abx123399
  • EUR 710.4
  • EUR 1028.4
  • EUR 493.2
  • 100 ul
  • 200 ul
  • 50 ul
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Antibody
20-abx339428
  • EUR 493.2
  • EUR 360
  • 100 ul
  • 50 ul
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Antibody
abx433110-200ul 200 ul
EUR 460.8
  • Shipped within 1-3 working days.

Podoplanin (PDPN) Antibody
20-abx005408
  • EUR 493.2
  • EUR 710.4
  • EUR 218.4
  • EUR 376.8
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul
  • Shipped within 5-10 working days.

Podoplanin (PDPN) Antibody
20-abx008317
  • EUR 360
  • EUR 526.8
  • EUR 226.8
  • 100 ul
  • 200 ul
  • 30 ul
  • Shipped within 5-10 working days.

Podoplanin Antibody gp36
R30481 100 ug
EUR 356.15
Description: Podoplanin is a protein that in humans is encoded by the PDPN gene. This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The International radiation Hybrid mapping consortium mapped the gene to chromosome 1. It is a typical type I membrane glycoprotein, with an N-terminal signal sequence, a signal sequence cleavage site, a C-terminal hydrophobic stretch, and a short cytoplasmic tail. It has been described as a differentiation antigen and influenza-virus receptor, and a marker of lung injury.

Podoplanin Antibody / gp36
R30760 100 ug
EUR 356.15
Description: PDPN (Podoplanin), also called T1A, T1A2, GP36, OTS8 or AGGRUS, is a protein that in humans is encoded by the PDPN gene. This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The PDPN gene is mapped to chromosome 1 by the International radiation Hybrid mapping consortium. The physiological function of PDPN may be related to its mucin-type character. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Immunohistochemical analysis of PDPN in placenta, kidney, lung, and nasal polyps showed expression at the apical plasma membrane of vascular endothelial cells and in alveolar epithelial cells. Overexpression of rat PDPN in human and rodent endothelial cells promoted formation of elongated cell extensions and significantly increased endothelial cell adhesion, migration, and tube formation. Inhibition of PDPN expression by small interfering RNAs decreased cell adhesion in cultured human dermal lymphatic endothelial cells.

Pdpn Antibody /Podoplanin
RQ6390 100 ug
EUR 356.15
Description: Podoplanin (PDPN) is a protein that in humans is encoded by the PDPN gene. This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The International radiation Hybrid mapping consortium mapped the T1A gene to chromosome 1. It has got 162 amino acid protein which is a typical type I membrane glycoprotein, with an N-terminal signal sequence, a signal sequence cleavage site, a C-terminal hydrophobic stretch, and a short cytoplasmic tail. Northern blot analysis detected a 1.2-kb T1A2 transcript only in lung. It has been described as a differentiation antigen and influenza-virus receptor, and a marker of lung injury.

Podoplanin Antibody / gp36
V3404-100UG 100 ug
EUR 349.3
Description: Podoplanin (PDPN) is a muco-protein which localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.
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